Table 4.
Serum levels of MDA, TAC, and hs-CRP among the study groups.
| Variable | Curcumin (n = 26) | Vitamin E (n = 27) | Placebo (n = 28) | P value E/P‡ |
|---|---|---|---|---|
| MDA (nmol/mL) | ||||
| Baseline† | 2.4 (0.9) | 2.4 (0.9) | 2.3 (1.29) | 0.920∗ |
| After 8 weeks† | 1.9 (0.6) | 2.2 (0.7) | 2.1 (1.0) | 0.993∗∗ |
| MD (95% CI) | −0.5 (−0.8 to −0.1) | −0.2 (−0.9 to 0.40) | −0.2 (−0.6 to 0.1) | |
| PP value | 0.009∗∗∗ | 0.195∗∗∗ | 0.230∗∗∗ | |
| TAC (mmol/L) | ||||
| Baseline† | 1.3 (0.3) | 1.3 (0.20) | 1.5 (0.3) | 0.820∗ |
| After 8 weeks† | 1. 5 (0.3) | 1.4 (0.20) | 1.6 (0.3) | 0.997∗∗ |
| MD (95% CI) | 0.2 (0.1 to 0.3) | 0.1 (0.01 to 0.2) | 0.05 (−0.01 to 0.1) | |
| PP value | <0.001∗∗∗ | 0.006∗∗∗ | 0.118∗∗∗ | |
| hs-CRP (mg/L) | ||||
| Baseline† | 5.1 (3. 4) | 4.9 (2.3) | 5.1 (3.3) | 0.998∗ |
| After 8 weeks† | 4.6 (2.6) | 4.8 (2.3) | 4.8 (3.3) | 0.861∗∗ |
| MD (95% CI) | −0.5 (−0.8 to −0.2) | −0.1 (−0.7 to 0.5) | −0.3 (−0.7 to 0.1) | |
| PP value | 0.025∗∗∗ | 0.718∗∗∗ | 0.219∗∗∗ | |
MDA: malondialdehyde, TAC: total antioxidant capacity, hs-CRP: high sensitivity C-reactive protein, MD: mean difference, CI: confidence interval; †mean (SD), P‡P value E/P: PP value of pairwise comparison between vitamin E and placebo groups, P§P value C/P: PP value of pairwise comparison between curcumin and placebo groups; ∗one-way ANOVA by Tukey, ∗∗analysis of covariance adjusted for baseline measures and confounding factors (vitamin C intake), ∗∗∗paired-samples t-test.