Table 2.
Myositis specific- and myositis associated autoantibodies stratified across the four JDM groups
| Patients total | Group 1 no organ involvement | Group 2 pulmonary only | Group 3 cardiac only | Group 4 coexisiting pulmonary and cardiac | |
|---|---|---|---|---|---|
| n | 57 | 12 | 35 | 4 | 6 |
| ANA IIF | 26 (46) | 6 (50) | 16 (46) | 1 (25) | 3 (50) |
| No MSA/ MAA | 38 (67) | 7 (58) | 23 (66) | 3 (75) | 5 (83) |
| Myositis specific autoantibodies | |||||
| Jo-1 | 1 (2) | 0 | 1 (3) | 0 | 0 |
| PL-7 | 1 (2) | 0 | 1 (3) 4 | 0 | 0 |
| SRP | 1 (2) | 1 (8) | 0 | 0 | 0 |
| Mi-2 | 3 (5) | 1 (8)1 | 2 (6) | 0 | 0 |
| NXP-2 | 5 (9) | 1 (8)3 | 3 (9)4 | 0 | 1 (25) |
| TIF1- γ | 1 (2) | 0 | 0 | 1 (25) | 0 |
| MDA5 | 2 (4) | 0 | 2 (6)5 | 0 | 0 |
| SAE-1 | 1 (2) | 1 (8)2 | 0 | 0 | 0 |
| HMGCR | 1 (2) | 1 (8)1 | 0 | 0 | 0 |
| Myositis associated autoantibodies | |||||
| PMScl75 | 3 (5) | 0 | 3 (9)6 | 0 | 0 |
| PMScl100 | 2 (4) | 0 | 2 (6)5 | 0 | 0 |
| Ku | 2 (4) | 1 (8) | 1 (3) | 0 | 0 |
| Ro52 | 3 (5) | 2 (17) 2,3 | 1 (3) 6 | 0 | 0 |
MSA Myositis specific autoantibodies, MAA Myositis associated autoantibodies, Numbers are n (%); No patients had detectable EJ, PL-12, OJ, SAE-2 or Mup44; 1,2,3,4,and 5denotes that more than one MSA and/or MAA are present in the same patient. IIF indirect immunofluorescence