Table 3.
Linear Mendelian randomization ratio of coefficient estimates.
| Biomarker | N | Hazard ratio (95% CI) | P-value |
|---|---|---|---|
| Serum iron | 56,654 | 1.07 (1.01–1.14) | 0.03 |
| Serum ferritin* | 2335 | 1.07 (0.26–4.41) | 0.92 |
| TSP | 56,651 | 1.07 (1.02–1.12) | 0.01 |
| TIBC | 56,654 | 0.96 (0.92–1.01) | 0.10 |
Hazard ratios with 95% confidence intervals for all-cause mortality are given per 1 standard deviation increase in the biomarker. Sample size (N), Confidence interval (CI), Transferrin saturation percentage (TSP), Total iron-binding capacity (TIBC).
*Measured in fertile, non-pregnant women, 20–55 years old, with no blood donations in the two previous years.