Table 4.
The MICs of samples at different pH and times and the MBCs (μg/mL) at different pHs.
| Bacterial strains | Samples | pH 5.5 | pH 7.4 | pH 10.5 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MIC (μg/mL) |
MBC (μg/mL) |
MIC (μg/mL) |
MBC (μg/mL) |
MIC (μg/mL) |
MBC (μg/mL) |
|||||
| 36 h | 18 h | 36 h | 18 h | 36 h | 18 h | |||||
| S. aureus (ATCC 25,923) | MWCNT-LVX | 19.531 | 39.062 | 78.125 | 39.062 | 78.125 | 156.25 | 78.125 | 78.125 | 312.5 |
| MWCNT-NH2 | – | – | – | – | – | – | – | – | – | |
| MWCNT-COOH | – | – | – | – | – | – | – | – | – | |
| LVX | 0.488 | 0.488 | 0.488 | 0.488 | 0.244 | 0.488 | 0.244 | 0.244 | 0.488 | |
| P. aeruginosa (ATCC 27,853) | MWCNT-LVX | 625 | 1250 | 1250 | 625 | 1250 | 1250 | 1250 | 1250 | 2500 |
| MWCNT-NH2 | – | – | – | – | – | – | – | – | – | |
| MWCNT-COOH | – | – | – | – | – | – | – | – | – | |
| LVX | 0.976 | 1.953 | 1.953 | 1.953 | 1.953 | 1.953 | 3.906 | 3.906 | 3.906 | |
Abbreviations: MIC: Minimum inhibitory concentration, MBC: Minimum bactericidal concentration, MWCNT: Multi-walled carbon nanotube, LVX: Levofloxacin, MWCNT-COOH: Carboxylic acid-functionalized MWCNT, MWCNT-NH2: Amine-functionalized MWCNT, MWCNT-LVX: Levofloxacine-loaded functionalized MWCNT.