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. 2022 Jun 16;13:3462. doi: 10.1038/s41467-022-31208-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — The number of distant eQTL (y-axis) in each 0.5 cM bin across the genome (x-axis) is shown. The horizontal dashed line indicates the threshold of 12 eQTL. Bins with 12 or more eQTL were identified as hotspots and are colored red. Adjacent bins that all passed the threshold were merged and are colored purple, with the center of the merged bins as the position on the x-axis. Bins with fewer than 12 eQTL are colored gray.