Skip to main content
. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: J Invest Dermatol. 2021 Dec 17;142(7):1812–1823.e3. doi: 10.1016/j.jid.2021.11.032

Figure 5: Model of fibroblast lineages, states, and fates for P0 neonatal skin.

Figure 5:

(a) Neonatal fibroblasts may transition to myofibroblasts states without rearranging chromatin landscapes. (b) The chromatin landscapes of neonatal papillary and reticular fibroblasts are poised to differentiate into dermal papilla and adipocytes. The rearrangement of chromatin landscapes between neonatal and papillary fibroblast lineages may support functional lineage restrictions.