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. 2022 Jun 16;12:10113. doi: 10.1038/s41598-022-14226-6

Table 2.

Summary of policy impacts derived from PSA.

Group Pre Expected post Observed post Change (95% CI) Difference-in-difference change (95% CI)
Non-ICU days PSP 4411 6481 5467  − 1013 [− 2051, − 24]  − 596 [− 942, − 276]
Non-PSP 682 847 793  − 55 [− 232, 120]
ICU days PSP 589 862 751  − 111 [− 309, 74]  − 172 [− 222, − 148]
Non-PSP 142 160 172 11 [− 30, 55]
Transfers PSP-mixed 140 209 139  − 70 [− 108, − 34]  − 83 [− 97, − 83]
Non-PSP 85 106 115 9 [− 15, 33]

Change column refers to the difference between observed and expected outcomes. Difference-in-difference analysis subtracts non-PSP change from PSP change.

IQR interquartile range reflecting 25th, 75th percentile of simulations, PSP Paediatric Sepsis Pathway, PSP-CH Children’s Hospital included in the PSP, PSP-mixed all participating PSP sites excluding PSP-CH.