Table 6.
Subgroup analyses for the association between childhood overweight/obesity and early puberty in boys.
| Subgroup | No. of studies | OR (95% CI) | I2 (%) | P -value for heterogeneity | Test for subgroup differences | ||
|---|---|---|---|---|---|---|---|
| χ2 | P -value | I2 (%) | |||||
| Geographic region | 0.36 | 0.55 | 0 | ||||
| Asia | 4 | 1.34 [0.97, 1.85] | 76 | 0.006 | |||
| North America | 1 | 1.07 [0.55, 2.09] | – | – | |||
| Sample size | 6.40 | 0.01 | 84.4 | ||||
| > 2,000 | 1 | 2.15 [1.31, 3.53] | – | – | |||
| ≤ 2,000 | 4 | 1.09 [0.93, 1.29] | 29 | 0.24 | |||
| Study design | 2.77 | 0.1 | 63.9 | ||||
| Cohort | 2 | 1.04 [1.00, 1.08] | 0 | 0.94 | |||
| Case-control | 3 | 1.61 [0.96, 2.68] | 72 | 0.03 | |||
| Confounders controlled | 12.31 | <0.001 | 91.9 | ||||
| None confounders controlled | 2 | 2.12 [1.43, 3.14] | 0 | 0.92 | |||
| One or more confounders controlled | 3 | 1.04 [1.00, 1.08] | 0 | 0.97 | |||