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. 2022 Jun 3;9:831541. doi: 10.3389/fmed.2022.831541

Table 2.

Comparison of the PUF, Total output, UV, Body weight and BP in PD patients before and after ARNI initiating.

Variables Before ARNI After ARNI Difference P-value
Abnormal distribution*
PUF, ml/24 h 389.1 (255.4, 536.6) 485.7 (318.6, 647.5) 66.4 (21.4, 123.2) 0.004
Total output, ml/24 h 836.3 (739.3, 919.3) 905.7 (807.9, 1,002.9) 81.1 (28.6, 139.3) 0.003
UV, ml/24 h 532.1 (418.6, 657.1) 520.0 (378.6, 670.7) 20.0 (−41.4, 61.4) 0.446
Normal distribution
Body weight, kg 60.0 (56.3, 63.8) 59.6 (56.0, 63.2) −0.4 (−0.7, −0.1) 0.005
SBP, mmHg 144.6 (139.0, 150.1) 138.7 (133.5, 143.5) −5.9 (−8.8, −3.0) <0.001
DBP, mmHg 91.9 (88.4, 95.5) 89.5 (85.9, 93.0) −2.4 (−4.6, −0.3) 0.030
*

Abnormal distribution, using Wilcoxon paired signed rank test, a non-parametric 95%CI and an estimator for the pseudo-median of the difference of the location parameters is computed. The calculation of the p-value was based on the range of pseudo-median of the distribution of difference. Accordingly, the data before and after ARNI were expressed as pseudo-median (95% CI).

Normal distribution, Using paired sample t-test, a 95%CI and an estimator for the mean of the difference is computed. The calculation of the p-value was based on the range of the mean of difference. Accordingly, the data before and after ARNI were expressed as mean (95% CI).

PUF, peritoneal ultrafiltration; UV, urine volume; BP, blood pressure; PD, peritoneal dialysis; ARNI, angiotensin receptor-neprilysin inhibitor; SBP, systolic blood pressure; DBP, diastolic blood pressure; CI, confidence interval.