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. 2022 Jun 16;12:10080. doi: 10.1038/s41598-022-14268-w

Figure 3.

Figure 3

3HBA enhances the gene expression levels of antioxidative stress factors, PPARγ, and lipogenic factors in vivo. (a) Schematic diagram of injection of 3HBA into C57BL/6 J male mice, including timeline for measurement of body weight and food intake, intraperitoneal injection of PBS or 3HBA, and sacrifice. (b) Body weight of PBS- and 3HBA-injected mice prefasting (− 12 h), postfasting (0 h), and postfeeding (12 h). n = 3. (c–f) Food intake (c), organ weight (d), blood glucose (e), and plasma 3HBA concentration (f) of PBS- and 3HBA-injected mice at 12 h postfeeding. n = 3. (g–m) qRT–PCR of antioxidative stress factors, such as SOD2 (g) and Catalase (h), PPARγ (i), and lipogenic factors, such as Acly (j), ACC (k), Fasn (l), and Scd1 (m), in epididymal adipose tissue from PBS- and 3HBA-injected mice at 12 h postfeeding. n = 3. Data are mean ± SEM. *p < 0.05, **p < 0.01.