Table 3.
Association between baseline depressive symptoms and risk of incident CKD and all-cause mortality.
| Model 1 a | Model 2 b | ||||
|---|---|---|---|---|---|
| Events/Total | HR (95%CI) | P-value | HR (95%CI) | P-value | |
| CKD | |||||
| Persistent | 243/492 | 1.512 (1.318 to 1.735) | <0.001 | 1.283 (1.061 to 1.552) | 0.010 |
| Episodic | 339/1,240 | 1.268 (1.128 to 1.425) | <0.001 | 1.093 (0.928 to 1.288) | 0.286 |
| No | 1,327/5,624 | Reference | Reference | ||
| Per 3-point increasec | 1.350 (1.258 to 1.449) | <0.001 | 1.178 (1.065 to 1.304) | 0.002 | |
| All-cause death | |||||
| Persistent | 148/492 | 1.567 (1.314 to 1.868) | <0.001 | 1.267 (0.991 to 1.620) | 0.059 |
| Episodic | 205/1,240 | 1.289 (1.106 to 1.503) | 0.001 | 1.226 (0.997 to 1.507) | 0.054 |
| No | 896/5,624 | Reference | Reference | ||
| Per 3-point increasec | 1.365 (1.242 to 1.501) | <0.001 | 1.246 (1.093 to 1.420) | <0.001 | |
aModel 1: adjusted for age and sex.
bModel 2: adjusted for age, sex, race, body mass index, hypertension, and diabetes.
cPer 3-point increasement of the mean CESD score at wave 7 and wave 8.