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. 2022 Jun 3;13:877896. doi: 10.3389/fimmu.2022.877896

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Copyright © 2022 Wang, Gao, Wang, He, Chen, Liu, Chen, Zhou, Chen, Yi, Xia and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential expression of pathways between C1 (wound healing)/C2 (IFN-γ dominant) vs. C3 (inflammatory) immune subtypes in LUAD patients. (A) Heatmap showing the different upregulation of gene set enrichment analysis (ssGSEA) of KEGG pathways among the C1 (wound healing) and C3 (inflammatory) immune subtypes in the TCGA LUAD cohort. (B) Heatmap showing the different upregulation of gene set mRNA enrichment analysis (ssGSEA) of KEGG pathways among the C2 (IFN-γ dominant) and C3 (inflammatory) immune subtypes in the TCGA LUAD cohort. The result is expressed according to the median z-scores of the ssGSEA score of pathways.