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. Author manuscript; available in PMC: 2023 Jun 1.
Published in final edited form as: Pediatr Crit Care Med. 2022 Mar 7;23(6):e277–e288. doi: 10.1097/PCC.0000000000002932

Table 5.

Multivariable model of factors associated with number of new medication classes or new device classes

Predictor Rate ratio
(95% Confidence Interval)
p-value
Number of new medication classes

Private insurance (Ref: government insurance) 1.65 (1.18, 2.31) 0.004
PICU length of stay (days) 1.01 (1.00, 1.02) 0.049
Neurologic insult(s) during PICU stay 1 1.74 (1.24, 2.46) 0.001

Number of new device classes

Pre-sepsis Functional Status Scale score 1.05 (1.01, 1.09) 0.007
Chemotherapy or radiotherapy within last 3 months 2.48 (1.34, 4.54) 0.005
Ventilation Duration (days) 0.030
  9 days or less Reference
  10+ days 1.52 (1.04, 2.22)
1

Neurologic insult was defined as pathologic breathing pattern, stereotypic posturing or flaccid posture, seizure activity and or abnormal electroencephalogram, new anoxic-ischemic injury on brain imaging, treatment for increased intracranial pressure, neurologic injury suspected by care provider, autonomic storming, or cardiopulmonary arrest or chest compressions.