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. 2022 Jun 3;13:875994. doi: 10.3389/fimmu.2022.875994

Table 1.

Main characteristics of the individuals enrolled in the study.

Characteristic Healthy controls RRMS relapse RRMS remission
Discovery set
 No. 10 10 10
 Female/male/P versus controls 6/4/P = 1.00 6/4/P = 1.00 6/4/P = 1.00
 Age, years, mean ± SD/P versus controls 35.8 ± 7.4/P = 1.00 35.2 ± 9.0/P = 0.93 32.4 ± 9.0/P = 0.80
 Disease duration, mean ± SD 4.7 ± 6.0 5.0 ± 6.4
 EDSS, mean ± SD 3.4 ± 1.9 2.4 ± 1.1
Validation set
 No. 27 18 27
 Female/male/P versus controls 21/6/P = 0.85 11/7/P = 0.22 19/8/P = 0.53
 Age, years, mean ± SD/P versus controls 34.7 ± 8.7/P = 1.00 36.8 ± 15.9/P = 0.85 36.3 ± 10.7/P = 0.85
 Disease duration, mean ± SD 6.5 ± 9.2 5.0 ± 5.7
 EDSS, mean ± SD 3.0 ± 0.8 1.5 ± 1.5