Table 1.

LncRNAs in PDAC development through EMT regulation.

LncRNA	Expression change in PDAC	Relevant target genes	Known molecular mechanisms	Reference
TUG1	Up	EZH2, SMAD1/2	CeRNA	(73, 74)
DYNC2H1-4	Up	ZEB1	CeRNA	(75)
ADPGK-AS1	Up	ZEB1	CeRNA	(76)
LINC00462	Up	TGFBR1/2	CeRNA	(77)
NORAD	Up	RhoA	CeRNA	(78)
Sox2ot	Up	Sox2	CeRNA	(79)
SNHG1	Up	FGFR1	CeRNA	(80)
H19	Up	SOCS5, STAT3	CeRNA	(81)
PMSB-8-AS1	Up	STAT1	CeRNA	(82)
OIP5-AS1	Up	FOXD1	CeRNA	(83)
PCED1B-AS1	Up	HIF−1α	CeRNA	(84)
LINC00958	Up	PAX8	CeRNA	(85)
MEG8	Up	SNAIL	CeRNA	(86)
GAS5	Down	SOCS3	CeRNA	(87)
XIST	Up	ZEB1,YAP	CeRNA	(88)
SNHG12	Up	miR-320b	CeRNA	(89)
RoR	Up	ZEB1	p53-ZEB pathway, Hippo/YAP pathway	(90, 91)
BX111	Up	HIF-1α,	Hypoxia-induced EMT	(92)
LINC01133	Up	EZH2	Wnt/β-catenin signaling	(93)
XLOC_000647	Up	NLRP3	Local regulators of its nearby gene	(94)
NT5E	Up	SYNCRIP	Local regulators of its nearby gene	(95)
HOTTIP	Up	HOXA13	Local regulators of its nearby gene	(96)
MALAT-1	Up	Sox2	Unknown	(97)
LINC00261	Up	E-cadherin	Unknown	(98)
PVT1	Up	P21	Unknown	(99, 100)
ANRIL	Up	ATM-E2F1	Unknown	(101)
MEG3	Up	SNAIL	Unknown	(102)
HOTAIR	Up	EZH2	Unknown	(103)
LINC01296	Up	SNAIL	Unknown	(104)
AL161431.1	Up	unknown	Unknown	(105)
PCTST	Down	E-cadherin and repressed vimentin	Unknown	(106)
SUMO1P3	Down	vimentin	Unknown	(107)