Table 2.

Target genes and functions.

Gene	Associated Function
Fcer1g	Limit CD8+ T cell expansion24
Ptma	Induce Th1 response25
Hspe1	Suppress T cell activation26 Involved in apoptosis86 Induce Tregs87
Tcea1	Proliferation, differentiation, and survival of myeloid cells27
Lyz2	Bacteriolytic enzyme found in macrophages88
C1qb	Drive macrophage polarization28,89
Srgn	Regulate secretion of inflammatory mediators and promotes tumor aggression29,30,90
Gzma	Induce apoptosis/cytolysis31
Tmsb4x	Cellular migration and repair32,91
Ccl5	Recruit hepatic leukocytes92
Cd52	Inhibit activation of NF-κB75
Slpi	Inhibition of neutrophil infiltration34
Il1b	Inflammatory cytokine93
Cxcr2	Neutrophil migration35
Rbm3	Induce apoptosis36
Aldoa	Infiltration of leukocytes37
Mt1	Alter the Th17/Treg balance38
Rgs1	Influence migration and autoimmunity39
Icos	T cell activation40
Cd28	T cell co-stimulatory molecule94
Ctla4	Immune cell infiltration and checkpoint41
Cd37	Dendritic cell migration42
Actb	Cytoskeleton housekeeping protein associated with cancer metastasis95
Cxcl10	Promote T cell-endothelial cell adhesion43
Rpl37a	Suppress tumor cell proliferation via p53 activation96