Table 2.

Top 30 differentially methylated positions (15 hypermethylated and 15 hypomethylated DMPs) in placental DNAs in GDM vs. euglycemic (control) groups.

CpG site	Chr	Gene	Gene group	Beta (GDM)	Beta (Control)	Delta beta	FDR
Hypermethylated
cg06295987	chr3			0.323	0.14	0.183	0.007
cg26380443	chr5	PCDHB15	1stExon	0.388	0.212	0.176	0.046
cg17010273	chr4	DKK2	TSS1500	0.373	0.205	0.169	0.019
cg03975200	chr6	FAM65B	TSS1500	0.711	0.546	0.165	0.047
cg07204602	chr10	CYP26C1	TSS1500	0.752	0.601	0.152	0.048
cg11423008	chr22	MIATNB	Body	0.775	0.627	0.149	0.024
cg15480311	chr21	ERG	Body; 5’UTR	0.519	0.391	0.128	0.039
cg25429559	chr3	CADM2	5’UTR;Body	0.858	0.732	0.126	0.041
cg06039355	chr10	GFRA1	5’UTR;TSS1500	0.441	0.321	0.12	0.007
cg26836456	chr1	DPYD	TSS1500	0.507	0.388	0.119	0.049
cg18414238	chr5	HCN1	Body	0.681	0.569	0.112	0.048
cg12189551	chr14	C14orf39	TSS200	0.261	0.15	0.112	0.042
cg16079012	chr3	SLC9A9	Body	0.744	0.635	0.109	0.049
cg17943876	chr5			0.552	0.445	0.107	0.007
cg05684050	chr5			0.775	0.67	0.106	0.04
Hypomethylated
cg16863522	chr2	DPP10	3’UTR	0.274	0.454	-0.18	0.017
cg27531336	chr8	PENK	TSS1500	0.276	0.433	-0.157	0.037
cg13112267	chr8	TSNARE1	Body	0.642	0.799	-0.157	0.046
cg13713677	chr12	WSCD2	TSS200	0.182	0.334	-0.152	0.028
cg05041928	chr4	LOC102723828	Body	0.561	0.697	-0.136	0.036
cg08664343	chr21			0.563	0.693	-0.13	0.028
cg26852437	chr11			0.561	0.69	-0.128	0.012
cg05581275	chr2	DPP10	Body	0.291	0.406	-0.115	0.012
cg13594075	chr2	NRXN	TSS200	0.411	0.526	-0.114	0.026
cg01097881	chr12	WSCD2	TSS200	0.25	0.362	-0.112	0.012
cg19502018	chr7	PDE1C	Body	0.583	0.695	-0.111	0.011
cg04831599	chr8			0.377	0.486	-0.109	0.03
cg24118713	chr12			0.634	0.741	-0.106	0.01
cg05474726	chr8	MIR124-2	TSS200	0.269	0.375	-0.106	0.04
cg10104921	chr4			0.491	0.596	-0.104	0.028

FDR, false discovery rate accounting for multiple tests.