Figure 2.

Wilms tumors have higher DNA repair scores than other pediatric cancer types, adult kidney cancer types, and matched normal kidney samples. (A) DNA repair scores in Wilms tumor and the other pediatric tumor types osteosarcoma, neuroblastoma, and rhabdoid tumor. (B) DNA repair scores in Wilms tumor and the other adult kidney tumor types chromophobe, papillary cell, and clear cell renal carcinoma. Two-way analysis of variance test. **, p<0.01; ****, p<0.0001. (C) Correlation between TIS and DNA repair score in Wilms tumor samples. Pearson’s correlation r=−0.389, p<0.0001. (D) DNA repair scores in Wilms tumor versus matched normal kidney samples. Two-sided paired t-test. ****, p<0.0001. TIS, tumor inflammation signature