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. 2022 Jun 15;10(6):e004797. doi: 10.1136/jitc-2022-004797

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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TIS significantly anti-correlates with DNA repair score in most TCGA tumor types, including melanoma. (A) Correlation coefficients for the correlation between TIS and DNA repair score in each TCGA tumor type. (B) Correlation between TIS and DNA repair score in TCGA metastatic melanoma samples. Pearson’s correlation r=−0.235, p<0.0001. (C) Correlation between TIS and GO_DNA repair gene score in TCGA metastatic melanoma samples. Pearson’s correlation r=−0.397, p<0.0001. TCGA, The Cancer Genome Atlas; TIS, tumor inflammation signature. SKCM: skin cancer, melanoma.