Table. Estimated Marginal Mean (95% CI) for Each Parameter Before, During, and After Spaceflight.
| Variable | Preflight seated | FD50 | FD150 | R + 10a | R + 30 | R + 180 |
|---|---|---|---|---|---|---|
| MRW, μm | 361.1 (330.4 to 391.8) | 381.7 (351.0 to 412.4) | 394.9 (364.1 to 425.4) | 378.3 (347.4 to 409.2) | 369.0 (338.3 to 399.7) | 358.9 (328.2 to 389.6) |
| Cup volume, mm3 | 0.193 (0.103 to 0.283) | 0.167 (0.077 to 0.258) | 0.158 (0.068 to 0.248) | 0.163 (0.072 to 0.253) | 0.177 (0.087 to 0.268) | 0.193 (0.103 to 0.284) |
| BMO height, μm | −118.3 (−147.1 to −89.4) | −124.7 (−153.5 to −95.8) | −127.2 (−156.1 to −98.3) | −117.2 (−146.4 to −88.0) | −118.4 (−147.3 to −89.5) | −122.3 (−151.2 to −93.4) |
| TRT250,b μm | 395.8 (376.4 to 415.1) | 407.8 (388.4 to 427.1) | 418.9 (399.5 to 438.2) | 411.7 (392.1 to 431.2) | 403.0 (383.7 to 422.4) | 393.7 (374.4 to 413.1) |
| TRT500,c μm | 371.8 (359.1 to 384.5) | 378.0 (365.3 to 390.7) | 384.0 (371.3 to 396.8) | 381.3 (368.5 to 394.1) | 376.2 (363.5 to 388.9) | 370.1 (357.4 to 382.8) |
| TRT1000,d μm | 338.0 (328.1 to 347.9) | 338.3 (328.4 to 348.2) | 340.0 (330.1 to 349.9) | 339.1 (329.1 to 349.1) | 339.3 (329.4 to 349.2) | 336.0 (326.1 to 346.0) |
| TRT1500,e μm | 302.5 (294.2 to 310.9) | 303.2 (294.8 to 311.5) | 302.7 (294.4 to 311.1) | 301.9 (293.5 to 310.3) | 302.6 (294.2 to 310.9) | 300.6 (292.3 to 309.0) |
| MT500,f μm | 272.4 (262.6 to 282.1) | 268.7 (258.9 to 278.4) | 267.2 (257.5 to 277.0) | 267.2 (257.4 to 277.0) | 269.9 (260.1 to 279.6) | 270.9 (260.1 to 279.6) |
| MT1500,g μm | 348.1 (339.4 to 356.8) | 345.5 (336.8 to 354.2) | 344.5 (335.8 to 353.2) | 344.7 (336.0 to 353.5) | 347.4 (338.7 to 356.1) | 347.0 (338.3 to 355.7) |
| MT2500,h μm | 315.7 (308.1 to 323.4) | 314.8 (307.1 to 322.4) | 314.7 (307.0 to 322.4) | 314.3 (306.6 to 322.0) | 316.1 (308.5 to 323.8) | 315.2 (307.6 to 322.9) |
Abbreviations: BMO, Bruch membrane opening; FD, flight day; MRW, minimum rim width; MT, macular thickness; R+, days after return to Earth; TRT, total retinal thickness.
a
The R + 10 time point includes only 8 participants, as several international crewmembers did not return directly to Houston.
b
TRT250, TRT from BMO to 250 μm.
c
TRT500, TRT from 250 to 500 μm.
d
TRT1000, TRT from 500 to 1000 μm.
e
TRT1500, TRT from 1000 to 1500 μm.
f
MT500, MT from the fovea to 500 μm.
g
MT1500, MT from 500 to 1500 μm.
h
MT2500, MT from 1500 to 2500 μm.