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. 2022 Feb 9;128(6):915–930. doi: 10.1016/j.bja.2022.01.012

Fig 3.

Fig 3

Interaction between the perioperative period and mosaic theory mechanisms causing higher blood pressure (BP). The diagram compares the response to surgery of normotensive (on the left) and hypertensive (on the right) patients, based on key mosaic theory-based mechanisms. Individuals with higher BP either fail to counteract or augment injurious pathways that are activated after major surgical tissue trauma.