Table 1:
Demographics and clinical characteristics by vasoactive medication exposure during the first postnatal week, 2009-2018
| Vasoactive med. exposure | p-value† | ||
|---|---|---|---|
| Yes N=10 070 |
No N=24 164 |
||
| Gestational age (weeks), N (%) | <0.001 | ||
| 22 | 328 (3) | 220 (0.9) | |
| 23 | 1868 (19) | 1612 (7) | |
| 24 | 2549 (25) | 3457 (14) | |
| 25 | 2201 (22) | 4649 (19) | |
| 26 | 1736 (17) | 6121 (25) | |
| 27 | 1388 (14) | 8105 (34) | |
| Birth weight (g), N (%) | <0.001 | ||
| <500 | 1176 (12) | 902 (4) | |
| 500-749 | 5243 (52) | 7933 (33) | |
| ≥750 | 3651 (36) | 15 329 (63) | |
| Male, N (%) | 5650 (56) | 12 403 (51) | <0.001 |
| SGA, N (%) | 2057 (21) | 2907 (12) | <0.001 |
| White race, N (%) | 3734 (39) | 9441 (41) | <0.001 |
| Cesarean section, N (%) | 7329 (74) | 16 721 (70) | <0.001 |
| 5 min. APGAR score <5, N (%) | 3502 (36) | 4607 (19) | <0.001 |
| Antenatal steroids, N (%) | 7922 (79) | 20 406 (84) | <0.001 |
| Mechanical ventilation, N (%)* | 9765 (97) | 19 125 (79) | <0.001 |
| Surfactant, N (%) | 9168 (91) | 19 535 (81) | <0.001 |
| Systemic corticosteroid, N (%)* | 2585 (26) | 601 (2) | <0.001 |
| Bacteremia, N (%)* | 528 (5) | 637 (3) | <0.001 |
*
Prior to postnatal day 7
†
p-value for Chi-squared test