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. 2021 Jul 19;33(6):1069–1079. doi: 10.1021/acs.bioconjchem.1c00203

Figure 1.

Figure 1

Schematic illustration of the proposed method. Tumor-targeted microbubbles are intratumorally injected into a tumor, followed by the application of low frequency focused ultrasound to detonate the microbubbles, reducing tumor cell viability and performing low energy mechanical ablation.