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. 2022 May 31;144(23):10151–10155. doi: 10.1021/jacs.2c03486

Table 2. Hydrolysis of Amidine 3Aa.

graphic file with name ja2c03486_0006.jpg

entry pH temp, °C buffer (500 mM) time 3A, % 5A, % 2A, %
1 7 20   30 days 100 0 0
2 7 80   18 h 34 15 36
3 7 80 PB 18 h 11 31 52
4 9 80 BB 18 h 0 38 61
a

PB = phosphate buffer, BB = borate buffer.