Table 1.
Baseline characteristics of study participants and levels of PA during accelerometer wear.
| No Incident Dementia (n = 35,279) | Incident Dementia (n = 283) | ||
|---|---|---|---|
|
|
|||
| Variables | Mean (SD) or n (%) | Mean (SD) or n (%) | p-value |
| Age (years) | 64.96 (3.28) | 67.43 (3.17) | <0.001 |
| Sex (Female) | 17,767 (50.36) | 124 (43.82) | 0.03 |
| Education (college or higher) | 14,116 (40.01) | 119 (42.05) | 0.53 |
| Townsend deprivation index | −2.04 (2.61) | −1.89 (2.73) | 0.39 |
| Ethnicity (white) | 34,765 (98.54) | 277 (97.88) | 0.50 |
| APOE genotype | <0.001 | ||
| 1 ε4 allele | 8,916 (25.27) | 120 (42.40) | |
| 2 ε4 alleles | 713 (2.02) | 29 (10.25) | |
| BMI (kg/m2) | 26.77 (4.2) | 26.88 (4.92) | 0.70 |
| Smoking status | <0.001 | ||
| never | 18,114 (51.34) | 129 (45.58) | |
| former | 15,335 (43.47) | 140 (49.47) | |
| current | 1,830 (5.19) | 14 (4.95) | |
| Alcohol | <0.001 | ||
| never | 4,640 (13.15) | 54 (19.08) | |
| moderate | 18,665 (52.91) | 143 (50.53) | |
| excessive | 11,974 (33.94) | 86 (30.39) | |
| Any Chronic condition (present) | 14,446 (40.95) | 125 (44.17) | 0.30 |
| General health | <0.001 | ||
| excellent | 7,433 (21.07) | 46 (16.25) | |
| good | 21,938 (62.18) | 158 (55.83) | |
| fair | 5,202 (14.75) | 57 (20.14) | |
| poor | 706 (2) | 22 (7.77) | |
| Depression (yes) | 12,124 (34.37) | 103 (36.4) | 0.51 |
| Healthy diet score (yes) | 20,540 (58.22) | 159 (56.18) | 0.53 |
| ACCave (mg) | 26.29 (7.38) | 23.29 (7.19) | <0.001 |
| PM2.5 absorbance | 1.09 (0.31) | 1.09 (0.32) | 0.42 |
| PM2.5 | 9.77 (1.28) | 9.85 (1.2) | 0.15 |
| PM10 | 15.95 (1.82) | 16.04 (1.87) | 0.02 |
| PM2.5-PM10 | 6.08 (0.75) | 6.07 (0.82) | 0.19 |
| NO | 39.99 (16.34) | 39.91 (15.85) | 0.32 |
| NO2 | 24.83 (10.11) | 24.88 (8.76) | 0.34 |
Note: air pollution variables are presented as median (interquartile range). P-values from t-tests or chi square tests comparing baseline characteristics in samples with and without incident dementia.