Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Possible mechansims leading to migaine progression. Hyperexcitabilty of neurons in trigeminal nociceptive pathway and other brian areas related to migraine patogeneisis plays important roles in migraine progression. Two main plausible mechanisms which can lead to this hyperexcitability are sensitization caused by repetitive and prolonged nociceptive activation, and the alteration in inhibitory control.
