Table 2.

Themes and illustrative quotes mapped to CFIR domains and constructs

CFIR Domains	CFIR Constructs	Themes	Illustrative Quotes
Intervention Characteristics	Complexity: −2	The complexity of intervention may lead to initial resistance to participation. Intervention logistics require streamlining.	“…Many patients thought it was too complex and complicated and did not accept it. Also, the logistics for tracking and keeping up with the box seemed to be complicated for the navigators as well. It could help if only one navigator oversaw the intervention….” MP Study Staff
		Indirect response reporting may be a drawback to data collection and accuracy	“…disadvantage with this intervention …is that it relies on indirect information (the person who received the kit) to give information on the person that they gave the kit to.” MP Study Staff
		Logistics regarding expiration and distribution timeframe need to be reassessed	“Don’t like that the kits expired… better if the kits were given out with more time. … would be happy to get more kits… have a lot of friends that would be interested!” MP Client
	Evidence Strength and Quality: +1	Positive perceptions of existing evidence supporting the need for intervention	“…a crucial part to the end of the HIV epidemic.” MP Study Staff
		Positive perceptions of the intervention’s efficacy and potential reach	“The intervention is effective …ability to have a large-scale reach within participants social networks.” MP Study Staff
		Positive perceptions of interventions ability to provide awareness and education	“…helps to reduce stigma around testing.” MP Client
	Adaptability: +2	Initial positive perceptions of the intervention with room for future adaptations	“…great concept theoretically and in-person. … many variables that can be modified and adapted to actual needs.” MP Study Staff
		Future adaptations needed to address difficulties due to COVID-19	“Consider delivery of the test kits because of COVID-19 to make it more convenient.” MP Client
Inner Setting	Relative Priority: +1	Positive perceptions of the implementation environment and community buy-in	“I think it is the perfect environment to implement an intervention like this one. The community surrounding is very supportive, and I believe it was very well received.” MP Study Staff
		Positive perceptions of the intervention within the community	“The community truly cares deeply…, so it aims to benefit our communities in Miami.” MP Study Staff
	Culture: +2	Community and MP clients appear well equipped to implement the intervention and have an adequate support network	“The system and the community surrounding are strong and cohesive as a network to implement the intervention. Mobile PrEP clients are knowledgeable about PrEP and testing and work as a strong peer support network.” MP Study Staff
Outer Setting	Patient Needs and Resources: +2	Tailored education needed for priority communities	“…people need more education on PrEP & HIV/STI, and more heterosexual people need education on HIV/STI and to think PrEP is an option.” MP Client
		Expansion into different methods to deliver education surrounding topics described in the intervention is needed	“Promote it more, how-to videos or more instructions.” MP Client
		Further promotion on effective prevention strategies and community resources will be extended	“…advertise more about PrEP and program services. Provide more education on HIV & PrEP.” MP Client
	External Policies and Incentives: −1	Negative impact on distribution due to COVID-19	“COVID-19 impacted distribution would like to receive more kits…” MP Client
Characteristics of Individuals	Individual Identification with the Program: +1	MP clients appear supportive of intervention and organizational values	“Those (Mobile PrEP clients) that are distributing the kits are very committed and dedicated to our organization, values, and mission.” MP Study Staff
	Self-Efficacy: +1	MP clients appear knowledgeable and prepared to further the implementation of the intervention within the community	“The Mobile PrEP clients who are distributing test kits to their social network are well equipped and knowledgeable about HIV testing and self-test kits. They are aware of the importance of testing and PrEP and are interested in acting as peer educators for the intervention.” MP Study Staff
	Knowledge and Beliefs about the Intervention: +1	MP clients appear willing to extend the intervention to SN members and identify populations in need of additional education	“…excited for the opportunity to help my friends because they had never been tested before. …more education for people that are not in the LGBTQI+ community about PrEP and HIV testing.” MP Client

Mobile PrEP clients (MP clients), Social Network Member (SN member)