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. 2022 Jun 16;20:284. doi: 10.1186/s12951-022-01479-6

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 7 — Gd-based NPs for triple-modal imaging. a Schematic of the structure of the MSC-platform. b TEM images of MSNs and HA-MSNs NPs. c The NIR fluorescence signal from ZW800 dye varied with an increase in MSCs concentration. d The increased T1 signal at the Orthotopic GBM mice model after MSC-platform administration for 24 h compared with pre-injection. e PET imaging of the MSC-platform and HA-MSN-⁶⁴Cu.

Reprinted with permission from [143]; copyright (2013) Elsevier Ltd.