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. 2022 Jun 17;20:92. doi: 10.1186/s12964-022-00888-2

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — High infiltration of tumor-associated macrophages in triple-negative breast cancer. A Representative immunohistochemical staining for CD163 in tissue sections from human breast cancer patients. B CD163 expression scores in breast cancer tissue sections. C CD163 expression in different types of breast cancer tissues. D Box-and-whisker plots showing the expression level of CD163 among normal, Her2⁺, luminal A, luminal B and basal-like subtypes. E–F Kaplan–Meier plots for the survival probability of all breast cancer patients with high or low CD163 expression in mRNA (E) and protein (F) levels, respectively