Table 5.
Effect of leaf extract and fractions of S. officinarum on rectal temperatures of mice infected with P. berghei during established infection.
| Treatment | Dose (mg/kg) | Rectal temperature (°C) | ||
|---|---|---|---|---|
| D0 | D3 | D7 | ||
| Control | – | 34.9 ± 0.5 | 35.2 ± 0.02 | 35.8 ± 0.1 |
| Extract | 170 | 34.7 ± 0.1 | 35.4 ± 0.10 | 35.8 ± 0.1 |
| 340 | 35.1 ± 0.3 | 35.3 ± 0.02 | 35.7 ± 0.1 | |
| 510 | 34.7 ± 0.2 | 35.3 ± 0.1 | 35.8 ± 0.1 | |
| n-Hexane fraction | 340 | 34.9 ± 0.3 | 35.3 ± 0.1 | 35.8 ± 0.1 |
| DCM fraction | 340 | 34.4 ± 0.1 | 35.3 ± 0.1 | 35.7 ± 0.04 |
| Ethyl acetate fraction | 340 | 35.0 ± 0.1 | 35.1 ± 0.03 | 35.7 ± 0.1 |
| n-Butanol fraction | 340 | 35.0 ± 0.2 | 35.3 ± 0.1 | 35.8 ± 0.1 |
| Chloroquine | 5 | 35.2 ± 0.3 | 35.4 ± 0.1 | 35.2 ± 0.1 |
Values are expressed as mean ± SEM, n = 6.