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. 2022 May 19;42(7):839–856. doi: 10.1161/ATVBAHA.122.317790

Figure 2.

Figure 2.

Atherosclerosis development at the aortic sinus and coronary arteries. Representative hematoxylin and eosin (H&E) stained pictures of atherosclerosis development at the aortic sinus of wild type (WT; A), apoE/apoA-I double deficient (DKO) mice overexpressing human apoA-I (DKO/hA-I; B), apoE deficient (EKO; C) and DKO mice (D). Representative oil red O (ORO) stained pictures of plaque development at the left atrioventricular valves of EKO (E) and DKO mice (F), and in the right coronary artery of EKO (G) and DKO mice (H). Magnifications of the same coronary plaques are shown (I and J). Atherosclerotic plaque quantification at the aortic sinus (K), number of plaques in coronary arteries and coronary branches (L), and average plaque length in coronary arteries (M) are also shown (n=6). Bar length: 250 μm. Statistically significant differences were determined by ANOVA followed by Tukey post hoc. *P<0.05; **P<0.01; and ***P<0.001. Precise adjusted P values are shown in Table S1.