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. 2022 May 31;13:779264. doi: 10.3389/fendo.2022.779264

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Copyright © 2022 Zhang, Zhao, Li, Geng, Zhao, Yang, Lv and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The correlation between clinical indicators and the incidence of OP. (A) 25(OH)D, CD4⁺CD25⁺ Treg cell and CD4⁺CD25⁺CD127^-/low Treg cell were found to decrease after the occurrence of OP. (B) RANKL/OPG, CD4/CD8, TNF-α and IL-6 were found to increase after the occurrence of OP.