Table 3.
PPV and NPV of clinical indicators from the ROC curve to predict the occurrence of osteoporosis.
| Test Result Variable(s) | Area | Std. Error | Asymptotic Sig. | Asymptotic 95% Confidence Interval | Cut off value | PPV | NPV | |
|---|---|---|---|---|---|---|---|---|
| Lower Bound | Upper Bound | |||||||
| 25(OH)D (ng/ml) | 0.812 | 0.055 | <0.001 | 0.705 | 0.919 | 14.75 | 94.81% (73/77) | 36.36% (16/44) |
| CD4+CD25+ (%) | 0.649 | 0.074 | 0.036 | 0.504 | 0.794 | 12.68 | 80.41% (78/97) | 4.17% (1/24) |
| CD4+CD25+CD127-/low (%) | 0.853 | 0.036 | <0.001 | 0.783 | 0.923 | 4.28 | 71.21% (47/66) | 1.82% (1/55) |
| RANKL/OPG (%) | 0.729 | 0.068 | 0.001 | 0.595 | 0.863 | 13.059 | 91.75% (89/97) | 50.00% (12/24) |
| CD4/CD8 | 0.549 | 0.083 | 0.490 | 0.387 | 0.711 | – | – | – |
| TNF-α (pg/ml) | 0.817 | 0.044 | <0.001 | 0.732 | 0.903 | 0.730 | 80.68% (71/88) | 9.09% (3/33) |
| IL-6 (pg/ml) | 0.751 | 0.050 | <0.001 | 0.653 | 0.850 | 4.93 | 84.00% (42/50) | 16.90% (12/71) |
25(OH)D, 25-hydroxyvitamin D; RANKL, receptor activator of nuclear factor-κB ligand; OPG, osteoprotegerin; TNF, tumor necrosis factor; IL, interleukin.