FIGURE 1.

Administration of BMSCs combined with FA ameliorates CCl₄-induced liver injury in rats. (A) The liver appearance of each group (normal, model, positive, BMSC, FA, and FC groups). (B) Comparison of body weight among the groups (Two-way ANOVA; *p < 0.05, **p < 0.01, ***p < 0.001 versus the normal group; #p < 0.05, ##p < 0.01, ###p < 0.001 versus the model group). (C,D) Serum levels of AST and ALT in each group (n = 6). Data are presented as the mean ± SEM (Two-way ANOVA; *p < 0.05 versus the normal group; #p < 0.05, ##p < 0.01 versus the model group). (E) Images of HE-stained liver sections from representative animals in the normal, model, positive, BMSC, FA, and FC groups (original magnification, ×10; scale bars, 100 µm, n = 6). (F) Masson stained liver sections from representative animals in the normal, model, positive, BMSC, FA, and BMSC&FA groups (original magnification, ×10; scale bars, 100 μm). The yellow squares indicate collagen. (G) The percentage of collagen area of Masson staining in each group (n = 6). Data are presented as the mean ± SEM (Two-way ANOVA; *p < 0.05 versus the normal group; #p < 0.05, ##p < 0.01, ###p < 0.001 versus the model group).