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. 2022 May 20;13:854327. doi: 10.3389/fimmu.2022.854327

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Copyright © 2022 Garlant, Ellappan, Hewitt, Perumal, Pekeleke, Wand, Southern, Kumar, Belgode, Abubakar, Sinha, Vasan, Joseph and Kempsell

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Combined box and scatter plot graphical depictions of composite panel score of the complex 6-plex biomarker panel between all controls and all active TB groups combined, displaying the cut-off value y=22361 for discrimination of all active TB groups from all controls with 90.1% sensitivity and 85.7% specificity (B) Combined box and scatter plot graphical depictions of expression of the complex 6-plex biomarker panel between individual control and active TB groups displaying the cut-off value y=19698 for discrimination of all active TB groups from all controls with 95.4% sensitivity and 81.3% specificity.