Skip to main content
. 2022 Jun 17;17(6):e0270105. doi: 10.1371/journal.pone.0270105

Table 2. Description of measures.

Measure Description
6-Minute Walk Test (m, 6MWT) Participants were instructed to walk as far as possible around a rectangular path for 6 minutes. The 6MWT is a valid and reliable test of walking endurance in persons with stroke [35, 36]. Evidence suggests that the 6MWT is a strong predictor of walking activity in individuals with stroke [3, 20, 26].
Self-selected walking speed (m/s, SSWS) Participants traverse a 10-meter pathway in which the middle 6 meters are timed. Participants are instructed to walk at a leisurely pace as if they were going to get a drink from the refrigerator. The 10-Meter Walk Test is a valid and reliable test of gait speed in stroke [36].
Fastest walking speed (m/s, FWS) Similar to the above, except participants are instructed to walk at the fastest speed they safely can without running [36].
Speed modulation (m/s) Speed modulation measures the ability to change walking speeds and was calculated as FWS–SSWS.
Montreal Cognitive Assessment (MoCA) The MoCA was collected as a global measure of cognitive impairment and assesses various domains, such as executive functioning and attention. The MoCA has acceptable sensitivity and specificity in detecting cognitive impairment in people with stroke [37].
Charlson Comorbidity Index (age adjusted, CCI) The CCI is a comorbidity index that inquires about other health conditions, such as myocardial infarction, diabetes, and congestive heart failure. The CCI has been shown to predict functional outcomes in individuals with stroke [38].
Patient Health Questionnaire-9 (PHQ-9) The PHQ-9 is a screening tool for depressive symptoms. It is a 9-item self-administered questionnaire that asks participants to reflect on how often they have been bothered by specific problems over the past two weeks. The PHQ-9 is a valid and reliable measure of depressive symptoms in stroke [39].
Activities Specific Balance Confidence Scale (ABC) The ABC is a 16-tem questionnaire that measures balance self-efficacy. Participants rate how confident they are performing various tasks on a scale of 0 (“no confidence”) to 100 (“complete confidence”). Ratings for each item are averaged to produce an overall score. The ABC is a valid and reliable measure in persons with stroke [40] and has been shown to be related to daily stepping activity in stroke [28, 29].
Body mass index (BMI, kg/m2) Body mass index was calculated as the participant’s weight in kilograms (kg) divided by height in meters (m) squared.
Age (years) Participant’s age was a continuous variable quantified in years.
Time since initial stroke (months) This variable was calculated as the time between initial stroke onset and the date of the baseline evaluation of the clinical trial. Participants were required to be at least 6 months post stroke to be eligible.
Number of strokes This was quantified as the number of strokes the participant suffered and was confirmed by imaging.
Number of medications (including supplements) This variable was quantified as the number of medications the participant reported taking, including supplements.
Area Deprivation Index (state decile) The ADI is a composite index of neighborhood disadvantage that includes various indicators of education, housing quality and crowding, poverty, and employment. The ADI provides a state decile ranking from 1 to 10 for each individual state, where 1 indicates the least disadvantaged and 10 the most disadvantaged [41, 42].
Area Deprivation Index (national percentile) The ADI also provides a national percentile ranking from 1–100, with 1 representing the lowest level of disadvantage and 100 representing the highest level of disadvantage [41, 42]. Our previous work identified a significant relationship between the ADI and steps/day in people with chronic stroke [31].
Usual orthotic device Usual orthotic device was a categorical variable coded as 0 = no orthotic device, 1 = orthotic device.
Usual assistive device Usual assistive device was a categorical variable coded as 0 = no assistive device, 1 = assistive device.
Living situation Living situation was a categorical variable coded as 0 = living alone, 1 = living with a family member/significant other, 2 = living alone but has outside assistance daily, 3 = other.
Marital status Marital status was a categorical variable coded as 0 = married, 1 = not married.
Work status Work status was a categorical variable coded as 0 = employed full-time, 1 = employed part-time, 2 = retired, 3 = unemployed (includes being on disability).
Years of education Years of education was a categorical variable coded as 0 = high school (≤15 years), 1 = college graduate (16 years), 2 = above graduate (>16 years).
Gender Gender was coded as 0 = male and 1 = female.
Side of hemiparesis Side of hemiparesis was categorized as 0 = left, 1 = right, 2 = bilateral.
Readiness to change activity behavior Readiness to change activity behavior was measured on an ordinal scale based on the Transtheoretical Model of Change [43, 44]. Participants endorsed a response that best reflected their current stage of change. This variable was categorized as 1 = currently not active and do not intend on becoming active in the next 6 months, 2 = currently not active but thinking about starting to become active in the next 6 months, 3 = currently active sometimes but not regularly, 4 = currently active regularly but have only begun doing so within the last 6 months, 5 = currently active regularly and have done so for longer than 6 months.
Relapse in activity behavior Relapse in activity behavior was measured via self-report and categorized as 1 = experienced a relapse in activity levels, 2 = no relapse in activity levels [43, 44].