Table 1. Summary of B. malayi adult parasitology in gerbils, CB.17 SCID mice and BALB/c IL-4Rα-/-IL-5-/- mice.
Strain | % active infection (n) | Median % adult recovery of L3 inoculate (range, n) | % infections producing males (n) | Average ratio F:M |
---|---|---|---|---|
Gerbil | 80.8 (105) | 4% (0–32.5, 105) | 65.4 (105) | 1:0.65 |
CB.17 SCID | 95.5 (88) | 13% (0–49, 88) | 92.1 (88) | 1:0.35 |
IL4Rα -/- IL-5 -/- | 95.9 (72) | 12% (0–59.3, 72) | 87.5 (72) | 1:0.34 |
Adult parasitology summary between rodent strains and species detailing: 1. the percentage of active infections as a function of the total number of animals of that species/strain infected (the percentage of animals with parasites retrieved at necropsy), 2. the median percentage of adults recovered (males and females) as a function of the initial L3 inoculate, 3. the percentage of total infections producing males as opposed to female only infections, and the average ratio of females to males across infections.