Skip to main content
. Author manuscript; available in PMC: 2023 May 3.
Published in final edited form as: Chem Commun (Camb). 2022 May 3;58(36):5490–5493. doi: 10.1039/d2cc01518h

Scheme 2.

Scheme 2

Synthesis of difluoroethanols 1015 by hydroxymethylation from the in situ generation of formaldehyde and difluorobenzyl carbanions, and synthesis of difluorodideuteroethanols 1618 by hydroxydeuteromethylation (percent deuterium incorporation is listed in brackets).