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. Author manuscript; available in PMC: 2022 Jun 17.
Published in final edited form as: Circ Cardiovasc Interv. 2020 Apr 13;13(4):e008587. doi: 10.1161/CIRCINTERVENTIONS.119.008587

Table 2.

Estimated change in MLD in μmeter for every 10μg change in Ach dosage

Slopes Women (estimates of MLD change/10µg Ach) Men (estimates of MLD change/10µg Ach)

Ach No endothelial dysfunction Endothelial dysfunction No endothelial dysfunction Endothelial dysfunction

doses >20µg −2.7 (−31.8 – 26.4) −21.6 (−47.4 – 4.2) 3.9 (−27.3 – 35.1) −37.4 (−63.8 – −11.0)
doses >50µg 9.5 (−4.4 – 23.3) 1.8 (−9.3 – 12.8) 16.1 (−0.67 – 32.8) −14.0 (−27.3 – −0.76)
doses >100µg −2.4 (−12.2 – 7.3) −2.9 (−14.9 – 9.1) 4.2 (−10.8 – 19.1) −18.7 (−32.3 – −5.1)

Slope estimates presented in µmeter/10µg; Ach = acetylcholine