Table 6.
DNA damage in different visceral organs of Labeo rohita (as observed by Comet assay) treated with various doses of pyriproxyfen.
| Parameters/days | Groups/treatment | |||
|---|---|---|---|---|
| T0 (0.0) | T1 (300 μg/L) | T2 (600 μg/L) | T3 (900 μg/L) | |
| DNA damage by comet assay in liver | ||||
| 10 | 2.35 ± 0.04 | 2.37 ± 0.05 | 2.39 ± 0.03 | 3.42 ± 0.14∗ |
| 20 | 2.37 ± 0.09 | 2.42 ± 0.06 | 3.47 ± 0.02∗ | 4.52 ± 0.19∗ |
| 30 | 2.43 ± 0.02 | 2.56 ± 0.02 | 4.70 ± 0.01∗ | 4.84 ± 0.22∗ |
| DNA damage by comet assay in kidneys | ||||
| 10 | 2.55 ± 0.19 | 2.67 ± 0.17 | 2.69 ± 0.27 | 4.47 ± 0.45∗ |
| 20 | 2.57 ± 0.21 | 2.72 ± 0.16 | 4.87 ± 0.51∗ | 5.53 ± 0.49∗ |
| 30 | 2.63 ± 0.25 | 2.76 ± 0.21 | 5.70 ± 0.61∗ | 5.81 ± 0.28∗ |
| DNA damage by comet assay in gills | ||||
| 10 | 2.23 ± 0.23 | 2.41 ± 0.11 | 2.51 ± 0.21 | 3.94 ± 0.44∗ |
| 20 | 2.31 ± 0.31 | 2.44 ± 0.14 | 3.87 ± 0.02∗ | 4.55 ± 0.39∗ |
| 30 | 2.23 ± 0.26 | 2.46 ± 0.12 | 4.77 ± 0.01∗ | 5.89 ± 0.42∗ |
In each row, values (Mean ± SE) bearing asterisks differ significantly (P ≤ 0.05) from that of values in untreated (T0 negative control) fish. T1, T2, and T3 are positive control and dose based.