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. 2022 Jun 17;12:10197. doi: 10.1038/s41598-022-14407-3

Table 2.

Treatment outcomes.

MLTD group (n = 13) Control group (n = 13) P value
MDZ dose, mg (IQR) 3 (3–4) 2.5 (2–4) 0.62
MucoUp dose, mL (IQR) 28 (15–40) 20 (16–40) 0.64
Maneuverability, n (%) 0.4
Good/normal 10 (76.9) 8 (61.5)
Poor 3 (23.1) 5 (38.5)
Poor submucosal lifting because of fibrosis, n (%) 1.0
Positive 0 (0) 0 (0)
Procedure time, min (IQR) 50 (33–63) 30 (23–55) 0.38
Dissection speed, mm2/min (IQR) 19.9 (14.4–26) 28.7 (17–35.7) 0.19
Specimen damage, n (%) 1.0
Yes 0 (0) 1 (7.7)
En bloc resection, n (%) 1.0
Yes 100 (13) 100 (13)
Resectabillity, n (%) 1.0
R0 100 (13) 100 (13)
Resected tumor size, mm (IQR) 30 (22–33) 24 (20–36) 0.92
Largest diameter of the resected specimen, mm (IQR) 43 (32–45) 34 (30–45) 0.74
Smallest diameter of the resected specimen, mm (IQR) 30 (22–33) 33 (24–38) 0.61
Final pathology, n (%)
Histology 0.12
 Adenoma 9 (69.2) 5 (38.5)
 Tub 4 (30.8) 8 (61.5)
 Por, sig, muc 0 (0) 0 (0)
Depth 0.29
 Tis 3 (23.1) 6 (46.2)
 T1a 1 (7.7) 2 (15.4)
 T1b 0 (0) 0 (0)
Intraoperative perforation, n (%) 1.0
Yes 0 (0) 0 (0)
Intraoperative bleeding, n (%) 1.0
Yes 0 (0) 0 (0)
Delayed perforation, n (%) 1.0
Yes 0 (0) 0 (0)
Delayed bleeding, n (%) 1.0
Yes 0 (0) 0 (0)
Surgery due to adverse events, n (%) 1.0
Yes 0 (0) 0 (0)
Recurrence, n (%) 1.0
Yes 0 (0) 0 (0)

IQR interquartile range, MZD midazolam.