Table 5.

Multivariate multiple logistic regression analyses of variables for GC metastasis.

	TNM stage II			TNM stage III			TNM stage IV
	Odds ratio	95% CI	P value	Odds ratio	95% CI	P value	Odds ratio	95% CI	P value
NLR	0.765	0.32–1.827	0.547	0.467	0.266–0.818	0.008	0.156	0.092–0.265	< 0.001
CEA	0.424	0.182–0.987	0.047	0.342	0.188–0.621	< 0.001	0.221	0.124–0.394	< 0.001
CA19-9	0.87	0.364–2.08	0.755	0.406	0.234–0.703	0.001	0.28	0.165–0.476	< 0.001
CA72-4	1.238	0.42–3.65	0.699	0.4	0.216–0.741	0.004	0.228	0.126–0.414	< 0.001

For multiple logistic regression analyses the reference category is TNM stage I. The reference of NLR, CEA, CA19-9 and CA72-4 was NLR ≥ 2.91, CEA ≥ 4.34, CA19-9 ≥ 18.69 and CA72-4 ≥ 6.96.

TNM tumor-node-metastasis, NLR neutrophil–lymphocyte ratio, CEA carcinoembryonic antigen, CA19-9 carbohydrate antigen 19-9, CA72-4 carbohydrate antigen 72–4.