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. 2022 Jun 17;12:10172. doi: 10.1038/s41598-022-14279-7

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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PDMS has a flexible characteristic that can mimic real blood vessels and is therefore used in the phantom model. In panel (a) and (b), we show the effect on the model before and during the surface is depressed with a thumb, respectively. The channels are filled with a blood like substance (water and food dye) and an external force reduces the size of the channel significantly (as indicated by arrows). Showing possible applications of these compliant phantom models, for example, as to simulate flow restrictions in blood vessels.