Table 2.

Risk of receiving no active anti-cancer treatment within the first four months after the diagnosis of localized and regional biliary tract cancer according to the tumor location.

	Gallbladder		Intrahepatic bile duct		Extrahepatic bile duct		Ampulla of Vater		All biliary tract cancer
	Risk ratio (95% CI)	P-value	Risk ratio (95% CI)	P-value	Risk ratio (95% CI)	P-value	Risk ratio (95% CI)	P-value	Risk ratio (95% CI)	P-value
Period
2006–2011	1		1		1		1		1
2012–2017	0.579 (0.460–0.728)	< 0.001	0.783 (0.699–0.878)	< 0.001	0.736 (0.640–0.845)	< 0.001	0.873 (0.628–1.213)	0.419	0.819 (0.804–0.833)	< 0.001
Age
00–59	1		1		1		1		1
60–69	1.413 (1.192–1.674)	< 0.001	1.237 (1.130–1.354)	< 0.001	1.303 (1.171–1.450)	< 0.001	1.861 (1.402–2.469)	< 0.001	1.313 (1.250–1.380)	< 0.001
70–79	2.579 (2.214–3.003)	< 0.001	2.010 (1.856–2.177)	< 0.001	2.361 (2.146–2.599)	< 0.001	4.562 (3.563–5.841)	< 0.001	2.435 (2.332–2.543)	< 0.001
≥ 80	4.785 (4.124–5.553)	< 0.001	2.925 (2.708–3.159)	< 0.001	3.890 (3.544–4.270)	< 0.001	11.114 (8.786–14.058)	< 0.001	4.416 (4.234–4.605)	< 0.001
Sex
Male	1		1		1		1		1
Female	1.030 (0.958–1.108)	0.417	1.033 (0.996–1.071)	0.084	1.069 (1.034–1.106)	< 0.001	1.020 (0.925–1.125)	0.687	1.009 (0.991–1.027)	0.313