Table 1.

Genes with the strongest positive and negative spatiotemporal correlations with OXTR.

Rank	Top correlated			Top anti-correlated
	Gene	Trajectory	Arithmetic	Gene	Trajectory	Arithmetic
1	FGFR3	0.368	0.365	DEPDC5	−0.381	−0.365
2	GRAMD1C	0.358	0.363	CACNA1A	−0.368	−0.382
3	C1orf88	0.356	0.358	KLC2	−0.363	−0.373
4	NTSR2	0.35	0.318	KCNC3	−0.363	−0.313
5	INHBB	0.348	0.328	C2CD3	−0.361	−0.319
6	CXorf59	0.343	0.348	HDAC8	−0.359	−0.345
7	KCNN3	0.341	0.336	CTCF	−0.349	−0.3
8	DIRAS3	0.34	0.286	MAP3K12	−0.347	−0.356
9	STON2	0.338	0.345	MICAL2	−0.345	−0.313
10	RDH10	0.335	0.338	APBA2	−0.345	−0.285
11	AGXT2L1	0.328	0.301	MORC2	−0.343	−0.334
12	SIL1	0.327	0.293	NOVA1	−0.341	−0.318
13	HRSP12	0.326	0.316	NFIX	−0.34	−0.321
14	GLUD1	0.323	0.309	KCNJ3	−0.338	−0.333
15	GNG12	0.323	0.32	KDM5C	−0.337	−0.345
16	PBXIP1	0.321	0.304	SEMA4C	−0.333	−0.315
17	RUNX3	0.319	0.289	EPS15L1	−0.332	−0.33
18	F3	0.317	0.312	TMEM25	−0.33	−0.325
19	ACSBG1	0.317	0.303	DHX8	−0.33	−0.307
20	GJA1	0.316	0.301	ADAM11	−0.329	−0.275

Two approaches for this analysis are presented. “Trajectory” represents a mean correlation across the lifespan trajectory, in which each life period receives an equal weighting. “Arithmetic” represents the mean of individual correlations between donors, in which each donor is weighted equally.