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. 2022 Jun 17;12:10265. doi: 10.1038/s41598-022-14535-w

Table 4.

Hazard ratio [95% confidence interval] for cardiovascular mortality based on presence or absence of echocardiographic abnormalities in patients with PVCs during recovery, n = 1327 (138 events).

Univariable analysis Multivariable analysisa Wald p
Increased E/e′ ratio 3.7 [2.6–5.3] 2.0 [1.4–3.0] 3.5 < 0.01
LV dilatation 3.6 [2.3–5.6] 2.2 [1.2–3.8] 2.6 0.01
Increased LV mass 2.6 [1.8–3.6] 1.7 [1.1–2.5] 2.6 0.01
Reduced LVEF 3.3 [2.2–4.8] 1.5 [1.0–2.5] 1.8 0.07
Increased RV/RA gradient 3.4 [2.2–5.3] 1.4 [0.9–2.6] 1.8 0.08
Moderate/severe aortic regurgitation 2.4 [1.4–4.4] 1.4 [0.8–2.6] 1.1 0.27
Moderate/severe mitral regurgitation 2.6 [1.7–3.8] 1.1 [0.7–1.9] 0.6 0.52
Increased LA diameter 2.6 [1.8–3.6] 1.0 [0.7–1.5] 0.0 0.98
Moderate/severe tricuspid regurgitation 1.7 [1.1–2.7] 0.9 [0.5–1.5] − 1.2 0.22
Moderate/severe aortic stenosis 1.1 [0.5–2.4] 0.6 [0.3–1.4] − 1.1 0.29

LA left atrial, LV left ventricle/ventricular, LVEF LV ejection fraction.

aHypertension, diabetes, ischemic heart disease, heart failure, body-mass index, use of either betablocker, angiotension-converting enzyme inhibitor, angiotension II blockers, loop diuretics, antihrombotics, anti-coagulants, or calcium channel blockers.