Table 3.
VLSM conjunction analysis for FMA-UL and TSRT in the entire cohort (n = 41).
| Areas | FMA-UL only | TSRT only | FMA-UL plus TSRT |
|---|---|---|---|
| Insula | 817 | 27 | 30 |
| Putamen | 284 | 30 | 18 |
| STG | 234 | 38 | 10 |
| EC | 146 | 35 | 26 |
| Heschl gyrus | 80 | 12 | |
| R. operculum | 25 | 76 | |
| SCR | 51 | 18a | |
| SLF | 32 | 12a | |
| IFO | 168 | ||
| Pallidum | 72 | ||
| PLIC | 43 | ||
| ACR | 35 | ||
| SS | 25 | ||
| UNC | 23 | ||
| RLIC | 20 | ||
| Temporal Pole Sup | 19 | ||
| MTG | 14 |
Number of voxels in affected brain regions where damage had a significant impact on FMA-UL only (z = 2.09 or higher), TSRT only (z = 2.09 or higher), and FMA-UL plus TSRT, in the entire cohort (n = 41). Only structures with at least 10 voxels affecting performance in one or more of the 3 options are shown.
FMA-UL Fugl-Meyer assessment scale for the upper limb, TSRT tonic stretch reflex threshold, ACR/SCR anterior/superior corona radiata, EC external capsule, IFO inferior fronto-occipital fasciculus, MTG middle temporal gyrus, PLIC/RLIC posterior/retro-lenticular limb of internal capsule, R. operculum Rolandic operculum, SLF superior longitudinal fasciculus, SS sagittal stratum, STG superior temporal gyrus, Temporal Pole Sup temporopolar region of STG, UNC uncinate fasciculus.
aThese structures did not appear in the VLSM analysis of the TSRT in Table 2 as at least 10 adjacent voxels had to show a statistically significant impact on performance for a cluster of voxels to be reported33,65,66.