A, Total KD patients for Kawasaki Disease Comparative Effectiveness Trial (KIDCARE) sites: 2018, 894 cases; 2019, 905 cases; 2020, 646 cases. There was a 27.7%-28.6% reduction in case numbers in 2020 compared with previous years. B, Incidence of KD by month of year at Rady Children’s Hospital San Diego during 2002 to 2019. Light blue line is the mean for 2002 to 2019, with errors bars indicating 2 SDs. Cases rebounded to close to within historic levels in late 2021.