Table 1.
Bioenergetic parameters in microglia: initial rates of glucose consumption and lactate production by isolated microglia (nmol/106 cells/min)
| Dosage impact | Lactate release (nmol/106 cells/min) | Oxidative ATP/glycolytic ATP | |||
|---|---|---|---|---|---|
| Basal | AA 5 μM |
∆-lactate (AA-basal ) | |||
| Control | 1.10 ± 0.03 | 2.45 ± 0.05 | 1.35 | 1.23 | |
| LPS | 0.1 μM | 1.50 ± 0.06* | 2.05 ± 0.07* | 0.55 | 0.36 |
| Aβ | 11 μM | 1.35 ± 0.05* | 2.15 ± 0.06* | 0.8 | 0.59 |
| 808 nm light | 10 J/cm2 | 1.10 ± 0.05 | 2.43 ± 0.07 | 1.34 | 1.24 |
| Aβ + 808 nm light | 1 μM + 10 J/cm2 | 1.2 ± 0.06 | 2.35 ± 0.08 | 1.15 | 0.95 |
The data are presented as the mean ± SD (n = 8 replicates in each group); *p < 0.05 indicates the data with a statistically significant difference (two-way ANOVA test)