Table 4.
Clinical characteristics and lipids levels of the study sample according to the degree of coronary artery stenosis and the Gensini scores system
| Categorical Variables | Coronary artery stenosis | Gensini scores | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| < 10% (n = 404) | 10–50% (n = 337) | 50–70% (= 402) | ≥ 70% (n = 212) | P value | 0–18 (n = 403) | 19–39 (n = 367) | 40–58 (= 385) | 59- (n = 196) | P value | |
| Sex, M (n%) | 165 (41%) | 159 (47%) | 236 (59%) | 136 (64%) | < 0.001 | 168 (42%) | 174 (47%) | 227 (59%) | 128 (65%) | < 0.001 |
| Age | < 0.001 | < 0.001 | ||||||||
| < 65 y | 245 (61%) | 152 (45%) | 177 (44%) | 87 (41%) | 242 (60%) | 168 (46%) | 169 (44%) | 78 (40%) | ||
| ≥ 65 y | 159 (39%) | 185 (55%) | 225 (56%) | 125 (59%) | 161 (40%) | 198 (54%) | 216 (56%) | 118 (60%) | ||
| Smoker (n%) | 100 (25%) | 98 (29%) | 153 (38%) | 75 (35%) | < 0.001 | 101 (25%) | 106 (29%) | 145 (38%) | 74 (38%) | < 0.001 |
| Drinker (n%) | 70 (17%) | 81 (24%) | 92 (23%) | 48 (23%) | 0.110 | 71 (18%) | 84 (23%) | 89 (23%) | 46 (24%) | 0.167 |
| DM (n%) | 49 (12%) | 88 (26%) | 102 (25%) | 79 (37%) | < 0.001 | 51 (13%) | 95 (26%) | 94 (24%) | 78 (40%) | < 0.001 |
| HTN (n%) | 208 (52%) | 124 (37%) | 119 (30%) | 67 (32%) | < 0.001 | 199 (49%) | 234 (64%) | 267 (69%) | 139 (71%) | < 0.001 |
| AH (n%) | 139 (35%) | 125 (37%) | 134 (33%) | 70 (33%) | 0.714 | 139 (35%) | 136 (37%) | 130 (34%) | 63 (32%) | 0.714 |
| HDU (n%) | 76 (20%) | 66 (20%) | 70 (18%) | 42 (20%) | 0.828 | 383 (95%) | 336 (92%) | 300 (78%) | 152 (78%) | 0.620 |
| BMI (kg/m2) | < 0.001 | < 0.036 | ||||||||
| < 18.5 | 19 (5%) | 9(3%) | 16(4%) | 12(6%) | 16(4%) | 9(3%) | 10(2.6%) | 10(6%) | ||
| 18.5–23.9 | 18 (45%) | 147 (44%) | 17 (43%) | 80 (39%) | 183 (45%) | 162 (44%) | 167 (43%) | 77 (39%) | ||
| 24.0–27.9 | 14 (35%) | 12 (36%) | 16 (41%) | 90 (44%) | 142 (35%) | 132 (36%) | 164 (43%) | 87 (44%) | ||
| ≥ 28.0 | 64 (19%) | 59 (18%) | 51 (13%) | 24 (12%) | 62 (15%) | 63 (17%) | 44 (11%) | 22 (11%) | ||
| LDL/HDL | 2.49 ± 0.83 | 2.20 ± 0.69 | 2.84 ± 1.02 | 3.13 ± 1.11 | < 0.001 | 2.48 ± 0.68 | 2.24 ± 0.73 | 2.90 ± 1.02 | 3.08 ± 1.13 | < 0.001 |
| LDL-C | < 0.001 | < 0.001 | ||||||||
| < 2.6 mmol/L | 173 (43%) | 191 (57%) | 162 (40%) | 84 (40%) | 176 (44%) | 200 (54%) | 147 (38%) | 84 (43%) | ||
| ≥ 2.6 mmol/L | 23 (57%) | 147 (44%) | 240 (60%) | 128 (60%) | 227 (56%) | 167 (45%) | 238 (62%) | 112 (57%) | ||
| HDL-C | < 0.001 | < 0.001 | ||||||||
| ≤ 1 mmol/L | 142 (35%) | 102 (30%) | 193 (48%) | 124 (59%) | 145 (36%) | 111 (30%) | 190 (49%) | 114 (58%) | ||
| > 1 mmol/L | 262 (65%) | 236 (70%) | 209 (52%) | 88 (42%) | 258 (64%) | 256 (70%) | 195 (51%) | 82 (42%) | ||
| TC | 0.182 | 0.205 | ||||||||
| < 5.2 mmol/L | 340 (84%) | 297 (88%) | 336 (84%) | 172 (81%) | 344 (85%) | 321 (87%) | 317 (82%) | 162 (83%) | ||
| ≥ 5.2 mmol/L | 63 (16%) | 41 (12%) | 64 (16%) | 40 (19%) | 59 (15%) | 46 (13%) | 68 (18%) | 34 (17%) | ||
| TG | 0.009 | 0.007 | ||||||||
| < 1.7 mmol/L | 298 (74%) | 250 (74%) | 268 (67%) | 135 (64%) | 298 (74%) | 270 (74%) | 251 (65%) | 127 (65%) | ||
| ≥ 1.7 mmol/L | 10 (26%) | 88 (26%) | 134 (33%) | 77 (36%) | 104 (26%) | 97 (26%) | 134 (35%) | 69 (35%) | ||
| Cr | < 0.001 | < 0.001 | ||||||||
| < 97 μmol/L | 368 (91%) | 306 (91%) | 333 (83%) | 157 (74%) | 363 (90%) | 332 (91%) | 324 (84%) | 140 (71%) | ||
| ≥ 97 μmol/L | 36 (19%) | 32 (10%) | 69 (17%) | 55 (29%) | 40 (10%) | 35 (9%) | 61 (16%) | 56 (29%) | ||
Values are expressed as mean ± standard deviation
M male, DM diabetes mellitus, HTN hypertension, AH arrhythmia history, HDU hypolipidemic drug use, LDL-C low-density-lipoprotein cholesterol, HDL-C high-density-lipoprotein cholesterol, LDL/HDL the ratio of low-density-lipoprotein to high-density-lipoprotein. BMI body mass index, TC total cholesterol, TG serum triglyceride, Cr serum creatinine